• Announcements

    • Admin

      Do you have a question?   01/27/2017

      Do you have any questions? Do you need information? Please let us know and we will try to help!
    • Admin

      Date Format and Registration   02/02/2017

      Registration & Date Format Please use the following: nn-nn-nnnn where n=number. For example, 6 June 1987: 06-06-1987 You must use "-" format and not "/"
    • Admin

      Blogs!   03/27/2017

      All registered Members can write their own Blog here! Just click on Blog and select a title!
    • Admin

      A new forum: chronic pain   04/27/2017

      We have a new forum called Chronic Pain. Articles, resources and management of pain.
    • Admin

      Registration and Validation   06/03/2017

      Thank you for your Registration! Validation is not automatic and will depend on time zone differences!It ought to be no more than 24 hours. If you do not hear within 24 hours, send me a message using the Contact Us! This is to try and prevent spammers, bots etc! Thank you and hope the LuPUS MB is useful to you!  
Admin

Screen for Anxiety, Mood Disorders in All Women With PCOS: Study

1 post in this topic

Screen for Anxiety, Mood Disorders in All Women With PCOS: Study

By Megan Brooks

NEW YORK (Reuters Health) Dec 16 - A new systematic review and meta-analysis shows that women with polycystic ovary syndrome (PCOS) are at higher risk for anxiety and depression.

"Clinicians should screen all women with the diagnosis of PCOS for anxiety disorders," first author Dr. Anuja Dokras of the University of Pennsylvania Medical Center, Philadelphia, told Reuters Health. "The association between anxiety disorders and PCOS is not well known."

Women with PCOS often have low self-esteem, poor body image, and fears about future health problems, including infertility, and perceived lack of effective treatment, all of which may make them anxious, Dr. Dokras and colleagues said in a November 29 online report in Fertility and Sterility.

Yet, only "limited data" exist on the prevalence of anxiety disorders in women with PCOS, the authors say.

From among 613 relevant articles they found nine studies from 2004-2010 that met their strict selection criteria.

Four studies had data on the prevalence of generalized anxiety symptoms in women with clearly defined PCOS and well-selected control women. The prevalence of anxiety was 20% in women with PCOS (42 of 206) vs. 4% in controls (8 of 204). "A variety of validated screening tools were used in the studies reporting the higher prevalence of anxiety symptoms," the authors note.

Women with PCOS had nearly a sevenfold increased risk of generalized anxiety symptoms (pooled odds ratio, 6.88). One study that matched controls on age and body mass index found 13-fold greater odds of anxiety with PCOS.

Most PCOS patients and control subjects in the reviewed studies were overweight or obese.

Of the five studies that reported average anxiety scores, three had significantly higher anxiety scores in women with PCOS compared with control women.

There was little information about other anxiety disorders, such as social phobia, panic attack, and obsessive compulsive disorder. Two of three studies reported a higher prevalence of social phobia in women with PCOS and one of two studies reported a higher prevalence of obsessive compulsive disorder.

Dr. Dokras and colleagues had previously reported that 35% of women with PCOS suffered from depression, a substantially higher rate than the 11% in control women.

Added to that, Dr. Dokras said, the new data suggest that "clinicians should now screen all women with PCOS for both anxiety and mood disorders" using validated screening tools.

Those found to have a mood disorder should be "referred for appropriate evaluation and/or use of psychologic and pharmacologic treatments," the researchers say.

They say more studies are needed to clearly define the prevalence of anxiety disorders in adolescents with PCOS, "given the early age of onset and chronic recurring nature of anxiety disorders."

"Future studies," they advise, "should be aimed at evaluating the association of common PCOS-specific characteristics, such as hyperandrogenism and infertility, with anxiety symptoms and disorders. This will help us to better understand why anxiety is more prevalent in women with PCOS and thereby to individualize therapies."

SOURCE: http://bit.ly/swahV3

Fertil Steril 2011.

Reuters Health Information © 2011

Share this post


Link to post
Share on other sites